MaRVis MR guidewires have been tested in a variety of animal trials for radiological and cardiological MRI-guided interventions. A list of publications can be obtained from MaRVis. Contact us!
A comprehensive MaRVis MR guidewire focused vessel model testing and animal trial has been performed by the group of Dr. Alexander Maßmann, Prof. Arno Bücker and Prof. Günther K. Schneider (Saarland University Medical Center, Homburg/Saar, Germany):
Glass-Fiber–based MR-safe Guidewire for MR Imaging–guided Endovascular Interventions: In Vitro and Preclinical in Vivo Feasibility Study
Alexander Massmann, Arno Bücker, Günther K. Schneider
Radiology. 2017 Aug;284(2):541-551. doi: 10.1148/radiol.2017152742. Epub 2017 Mar 16.
A total of 1,296 cannulations and 27 stent deployments plus other interventional procedures have been performed.
The authors reported: “MR imaging guidewires were characterized by good to excellent visibility, with a continuous artifact of 2 mm in diameter and 4 x 8 mm ball-shaped tip marker. Stiffness, flexibility, and guidance reflected comparable times for all in vitro and in vivo procedures with both the MR imaging and standard Nitinol guidewires. Standard and micro MR imaging guidewires were most suitable for the iliac crossover maneuver. Phantom visceral artery cannulation was easier with standard and micro MR imaging guidewires. The stiff MR imaging guidewire provided the best support for cannulation of the swine aorta and vena cava. All interventional procedures were performed successfully without complications.”
The authors concluded “that the use of glass-fiber–based guidewires for evaluation of MR imaging–guided endovascular interventions is technically feasible and safe in a swine model, and potentially, in humans.”
This independent work was recognized in 2018 with the Werner Porstmann prize, which is awarded by the German Röntgen Society for the best scientific work within the last two years in the field of interventional radiology.
Vessel model testing:
left: 0.014” micro MaRVis Guidewire with Cobra 4F catheter
right: 0.035” standard MaRVis Guidewire with Optimed sinus-SuperFlex-Visual 5F stent
Dr. Alexander Maßmann, Prof. Günther K. Schneider, Prof. Arno Bücker (Saarland University Medical Center, Homburg/Saar, Germany)